IV Semester (Molecular Genetics)
1. Chemical basis of Heredity
- DNA as genetic material, Experiment of Griffith, Avery, MacLeod, Mc Carry & Hard hey chase
- RNA as genetic Material-Experiment of Frankel & Singer
2. Nucleic Acids
- DNA structure & Types
- RNA structure & Types
- Ribozymes
3.DNA Replication
- DNA replication in prokaryotes & Rolling circle Model
- DNA replication in Eukaryotes
4. Gene Expression
- Genetic code: Brief introduction
- protein synthesis in prokaryotes & Eukaryotes translation
-- Transcription ("rho" dependent & "rho" independent Termination)
-- Post transcriptional modifications
-- Translation
- Regulation of Gene Expression
--- inducible operons-Galactose
--- Repressible operon - Tryptophan
5. Genome organisation & fine structure of the gene
- Prokaryotic genome - chromosomal & plasmid
- Eukaryotic genome-chromosomal & organellar
- Fine structure of the Gene - Cistron, Moton & Recon
6. Transposable elements
-- Maize & Drosophila
7. Bacterial Genetics
-- Transformation
-- Transduction - Generalized & specialized
-- Conjugation - F- Factor mediated, Hfr & sexduction
8. Mutations
-- Introduction & Types of Gene Mutation - Base substitution, Frame shift mutation ( insertion, deletion, missence, nonsense mutation)
-- Mutagens - Physical & chemical
-- Reverse mutation in bacteria, DNA repair mechanism (mismatch repair, photoreactivation, Excision & SOS repair).
-- Beneficial & harmful effects of mutation.
9. Introduction to Genomic & Proteomics.
1. Chemical basis of Heredity
- DNA as genetic material, Experiment of Griffith, Avery, MacLeod, Mc Carry & Hard hey chase
- RNA as genetic Material-Experiment of Frankel & Singer
2. Nucleic Acids
- DNA structure & Types
- RNA structure & Types
- Ribozymes
3.DNA Replication
- DNA replication in prokaryotes & Rolling circle Model
- DNA replication in Eukaryotes
4. Gene Expression
- Genetic code: Brief introduction
- protein synthesis in prokaryotes & Eukaryotes translation
-- Transcription ("rho" dependent & "rho" independent Termination)
-- Post transcriptional modifications
-- Translation
- Regulation of Gene Expression
--- inducible operons-Galactose
--- Repressible operon - Tryptophan
5. Genome organisation & fine structure of the gene
- Prokaryotic genome - chromosomal & plasmid
- Eukaryotic genome-chromosomal & organellar
- Fine structure of the Gene - Cistron, Moton & Recon
6. Transposable elements
-- Maize & Drosophila
7. Bacterial Genetics
-- Transformation
-- Transduction - Generalized & specialized
-- Conjugation - F- Factor mediated, Hfr & sexduction
8. Mutations
-- Introduction & Types of Gene Mutation - Base substitution, Frame shift mutation ( insertion, deletion, missence, nonsense mutation)
-- Mutagens - Physical & chemical
-- Reverse mutation in bacteria, DNA repair mechanism (mismatch repair, photoreactivation, Excision & SOS repair).
-- Beneficial & harmful effects of mutation.
9. Introduction to Genomic & Proteomics.
CLICK REFERENCE
Genetics
Paper 6 Human
Genetics
Paper8 Genetics
(Applied Genetics)
BIOCHEMISTRY
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